Boron containing metabolites are found in plants, algae and microorganisms. Boron forms complexes with fatty acids, such as borophycin, aplasmomycin, and tartrolon, and their derivatives. All these metabolites are polyketide antibiotics and are of great interest for medicine, and the pharmaceutical industry. In this paper, using the PASS computer program, we computed new biological activities for boron compounds. The results obtained show that fifty biologically active boron compounds show anti-cancer, antibacterial, and antifungal activity, with a confidence of 50 to 90 percent.